Schaller M D, Waeber B, Nussberger J, Bussien J P, Hofbauer K G, Brunner H R
Schweiz Med Wochenschr. 1984 Dec 8;114(49):1844-5.
The authors demonstrate that skin vasoconstriction induced by cigarette smoking in normal volunteers is due to a concomitant enhancement of arginine vasopressin release. The skin blood flow reduction after smoking was more pronounced in the subjects reaching the highest levels of arginine vasopressin, and this effect no longer developed after administration of a specific vasopressin antagonist acting at the vascular site.
作者表明,正常志愿者中吸烟引起的皮肤血管收缩是由于精氨酸加压素释放同时增强所致。在精氨酸加压素达到最高水平的受试者中,吸烟后皮肤血流减少更为明显,并且在给予作用于血管部位的特异性加压素拮抗剂后,这种效应不再出现。