Waeber B, Schaller M D, Nussberger J, Bussien J P, Hofbauer K G, Brunner H R
Clin Exp Hypertens A. 1984;6(10-11):2003-6. doi: 10.3109/10641968409046117.
In a study carried-out in double-blind fashion it was possible to demonstrate that skin vasoconstriction induced by cigarette smoking in normal volunteers is due to a concomitant enhancement of arginine vasopressin release. The skin blood flow reduction occurring after smoking was indeed more pronounced in the subjects reaching the highest levels of arginine vasopressin and this effect was curtailed by the administration of a specific vasopressin antagonist acting at the vascular site.
在一项采用双盲方式进行的研究中,有可能证明正常志愿者中吸烟引起的皮肤血管收缩是由于精氨酸加压素释放同时增强所致。吸烟后出现的皮肤血流量减少在精氨酸加压素水平达到最高的受试者中确实更为明显,并且这种效应通过给予作用于血管部位的特异性加压素拮抗剂而受到抑制。