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空回肠旁路术后患者对低分子量聚乙二醇(PEG 400)的肠道通透性降低。

Reduced intestinal permeability to low-molecular-weight polyethyleneglycols (PEG 400) in patients with jejunoileal bypass.

作者信息

Sundqvist T, Magnusson K E, Larsson L, Tagesson C, Backman L, Nordenvall B

出版信息

Acta Chir Scand. 1984;150(7):567-71.

PMID:6516679
Abstract

The intestinal permeation and 6-hour urinary recovery of small, multisized tracers, polyethyleneglycol 400 (PEG 400), was used to characterize gut permeability in nine patients after bypass surgery for morbid obesity and in ten healthy volunteers. In the patients, who also had hyperoxaluria, the urinary recovery of ingested PEG 400 was lower than in the healthy persons (10.9 and 24.7%). The patients also showed stronger intestinal exclusion of the larger polymers within the PEG 400.

摘要

采用小的、多种尺寸的示踪剂聚乙二醇400(PEG 400)的肠道渗透及6小时尿液回收率,对9例病态肥胖症旁路手术后患者和10名健康志愿者的肠道通透性进行了表征。这些患者还患有高草酸尿症,摄入的PEG 400的尿液回收率低于健康人(分别为10.9%和24.7%)。患者对PEG 400中较大聚合物的肠道排除作用也更强。

相似文献

1
Reduced intestinal permeability to low-molecular-weight polyethyleneglycols (PEG 400) in patients with jejunoileal bypass.空回肠旁路术后患者对低分子量聚乙二醇(PEG 400)的肠道通透性降低。
Acta Chir Scand. 1984;150(7):567-71.
2
Complex pathogenesis of hyperoxaluria after jejunoileal bypass surgery. Oxalogenic substances in diet contribute to urinary oxalate.空肠回肠旁路手术后高草酸尿症的复杂发病机制。饮食中的草酸生成物质会导致尿草酸增加。
Gastroenterology. 1983 Feb;84(2):293-300.
3
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