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钙在肥胖症空肠回肠旁路术后腹泻和高草酸尿症治疗中的应用

Calcium in the treatment of diarrhoea and hyperoxaluria after jejunoileal bypass for obesity.

作者信息

Stokholm K H, Abildgaard U

出版信息

Int J Obes. 1980;4(2):105-10.

PMID:7399801
Abstract

Fourteen patients with jejunoileal bypass for obesity were treated for one week with a calcium supplement of 3g daily. During this period diarrhoea was significantly (P < 0.005) reduced by 23 per cent (97 per cent confidence limits: 7-46 per cent). Ten of the patients had hyperoxaluria (median value 961 mumol/24 h; range 633-2742 mumol/24 h). The treatment with calcium significantly (P < 0.005) decreased the concentration of oxalate in urine by 23 per cent (98 per cent confidence limits: -5-+54 per cent). The calcium supplement did not increase urinary calcium-excretion rate or albumin-corrected serum calcium.

摘要

14名接受空肠回肠分流术治疗肥胖症的患者,每天服用3克钙补充剂,为期一周。在此期间,腹泻显著(P < 0.005)减少了23%(97%置信区间:7%-46%)。其中10名患者患有高草酸尿症(中位数为961μmol/24小时;范围为633-2742μmol/24小时)。补钙治疗使尿草酸浓度显著(P < 0.005)降低了23%(98%置信区间:-5%至+54%)。钙补充剂并未增加尿钙排泄率或白蛋白校正后的血清钙。

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