Schnabel E, Kriz W
Anat Embryol (Berl). 1984;170(2):217-22. doi: 10.1007/BF00319007.
The extraglomerular mesangial cell field was studied by morphometric techniques in volume expanded and volume depleted rats. The volume density of the extraglomerular mesangial interstitium was found to be significantly different between the two conditions, 16.9 +/- 3.7% in volume depletion and 29.0 +/- 4.1% in volume expansion. No difference in the volume density of the peritubular interstitium could be detected under the same conditions. These findings are interpreted as indicating a specific sensitivity of the extraglomerular mesangial interstitium to changes in body fluid content, a phenomenon which may play a role in the mechanism of resetting the tubulo-glomerular feedback control.
采用形态计量学技术，对容量扩张和容量减少的大鼠的球外系膜细胞区域进行了研究。结果发现，两种情况下球外系膜间质的容积密度存在显著差异，容量减少时为16.9±3.7%，容量扩张时为29.0±4.1%。在相同条件下，未检测到肾小管周围间质容积密度的差异。这些发现被解释为表明球外系膜间质对体液含量变化具有特定敏感性，这一现象可能在肾小管-肾小球反馈控制的重置机制中发挥作用。
