Occelli G, Saban Y, Pruneta R M, Pourcher N, Michel A M, Maestracci P
Ann Fr Anesth Reanim. 1984;3(6):440-2. doi: 10.1016/s0750-7658(84)80142-2.
Following two cases of anaphylactoid reactions during anaesthesia, immunoallergological investigations showed up the responsibility of droperidol, which probably acted by way of an anaphylactic mechanism. In both cases, there were no cardiovascular signs, the main clinical symptom being bronchospasm. The exceptional nature of allergic accidents due to neuroleptic drugs, as opposed to extrapyramidal phenomena, must be underlined. However, these reactions should cast doubts on the safety and usefulness of neuroleptanalgesia.
在两例麻醉期间发生类过敏反应的病例中，免疫过敏学调查显示氟哌利多是罪魁祸首，其可能通过过敏机制起作用。在这两例病例中，均无心血管体征，主要临床症状为支气管痉挛。必须强调的是，与锥体外系现象不同，抗精神病药物引起的过敏事故具有特殊性。然而，这些反应应使人对神经安定镇痛的安全性和有效性产生怀疑。
