必需脂肪酸对前列腺素生物合成的影响。
Effects of essential fatty acids on prostaglandin biosynthesis.
作者信息
Horrobin D F, Manku M S, Huang Y S
出版信息
Biomed Biochim Acta. 1984;43(8-9):S114-20.
PMID:6517895
Abstract
Prostaglandins (PGs) are derived from dietary essential fatty acids (EFAs) by relatively short biochemical pathways. PG synthesis can be manipulated by modifying EFA intake. PGs and related compounds of the 1 and 3 series have desirable or neutral actions while those of the 2 series are mixed, some being desirable but others being highly undesirable. Methods for selectively increasing 1 and 3 series products while simultaneously reducing the formation of arachidonic acid derivatives are described.
摘要
前列腺素（PGs）由膳食必需脂肪酸（EFAs）通过相对较短的生化途径衍生而来。通过改变必需脂肪酸的摄入量可以调控前列腺素的合成。1系列和3系列的前列腺素及相关化合物具有有益或中性作用，而2系列的则好坏参半，有些有益，有些则非常有害。本文描述了选择性增加1系列和3系列产物同时减少花生四烯酸衍生物形成的方法。
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