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对猝死婴儿和因婴儿猝死综合征(SIDS)濒死而住院的婴儿的病史进行批判性比较。

A critical comparison of the history of sudden-death infants and infants hospitalised for near-miss for SIDS.

作者信息

Kahn A, Blum D, Hennart P, Sellens C, Samson-Dollfus D, Tayot J, Gilly R, Dutruge J, Flores R, Sternberg B

出版信息

Eur J Pediatr. 1984 Dec;143(2):103-7. doi: 10.1007/BF00445795.

Abstract

To determine whether significant historical differences distinguish the near-miss for Sudden Infant Death from the infants who died of SIDS, we analysed the histories and clinical data from two groups of infants seen in our University Hospital and from collaborative research group. The data were obtained with the use of a standardised questionnaire and consultation of all available medical data. Sixty-five infants were identified as near-miss for SIDS after they had suffered a severe cardiorespiratory incident during sleep for which no cause could be found despite a complete medical examination. After an autopsy had failed to reveal a cause for the unexpected death 95 cases of SIDS were retained in the study. A series of 353 variables were collected from the parents, the gynaecologists, neonatologists and attending physicians. After statistical analysis, only 15 of the 353 items studied significantly differentiated between the two groups. A step-wise discriminant analysis performed on these items led to the identification of six independent variables: the time of the incident; the circumstances leading to the observation of the child; the child's sleep position; previous minor intestinal problems; the size of the family and the mother's coffee consumption. Most variables indicate that the near-miss infants were discovered and rescued earlier than the infants who died. No other historical information appeared significantly to differentiate between the two groups of infants. These data need confirmation from a prospective epidemiological survey.

摘要

为了确定婴儿猝死综合征(SIDS)的濒死情况与死于SIDS的婴儿之间是否存在显著的历史差异,我们分析了在我校医院就诊的两组婴儿以及合作研究组的病史和临床数据。数据通过使用标准化问卷以及查阅所有可用的医疗数据获得。65名婴儿在睡眠中发生严重心肺事件后被确定为SIDS濒死情况,尽管进行了全面的医学检查,但仍未找到病因。在尸检未能揭示意外死亡的原因后,95例SIDS病例被纳入研究。从父母、妇科医生、新生儿科医生和主治医生那里收集了一系列353个变量。经过统计分析,在研究的353个项目中,只有15个在两组之间有显著差异。对这些项目进行逐步判别分析后,确定了六个独立变量:事件发生时间;发现孩子的情况;孩子的睡眠姿势;既往轻微肠道问题;家庭规模以及母亲的咖啡摄入量。大多数变量表明,濒死婴儿比死亡婴儿更早被发现并获救。没有其他历史信息在两组婴儿之间表现出显著差异。这些数据需要前瞻性流行病学调查的证实。

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