Gordon T P, Sage M R, Bertouch J V, Brooks P M
J Rheumatol. 1984 Dec;11(6):794-7.
Computed tomography (CT) was used to delineate the paraspinal musculature in 14 patients with ankylosing spondylitis (AS). Abnormal atrophy of the erector spinae muscles and multifidi was demonstrated in all 8 patients with total bony ankylosis of the spine, but was not present in those with isolated syndesmophyte formation, vertebral squaring alone or sacroiliac joint ankylosis with normal spinal radiographs. There was a significant positive correlation between a CT score of paravertebral muscle wasting and clinical parameters of disease duration and restriction of spinal mobility. Wasting and asymmetry of the psoas muscles was seen in 3 patients with unilateral hip joint involvement. These findings suggest that a relationship exists between decreased or absent spinal movement and atrophy of the paraspinal musculature in AS.
采用计算机断层扫描（CT）对14例强直性脊柱炎（AS）患者的椎旁肌肉组织进行描绘。在所有8例脊柱完全骨性强直的患者中均显示竖脊肌和多裂肌存在异常萎缩，但在单纯有韧带骨赘形成、仅有椎体方形变或骶髂关节强直而脊柱X线片正常的患者中未出现。椎旁肌肉萎缩的CT评分与病程及脊柱活动受限的临床参数之间存在显著正相关。3例单侧髋关节受累的患者出现腰大肌萎缩和不对称。这些发现提示，AS患者脊柱活动减少或缺失与椎旁肌肉组织萎缩之间存在关联。
