博来霉素与肌苷联合应用对人横纹肌肉瘤-肉瘤化疗作用的增强
Potentiation of the chemotherapeutic action of bleomycin by combination with inosine on HRS-sarcoma.
作者信息
Osswald H, Youssef M
出版信息
Cancer Lett. 1975 Sep;1(1):55-8. doi: 10.1016/s0304-3835(75)95161-7.
PMID:65212
Abstract
The chemotherapeutic action of Bleomycin, applied at a dosage which induced only a non-specific tumor inhibition on HRS-sarcoma, was potentiated by combination with inosine. This combination, without increasing toxicity, effected both a significant tumor inhibition and a significant curative action.
摘要
博来霉素在对HRS肉瘤仅产生非特异性肿瘤抑制作用的剂量下，与肌苷联合使用可增强其化疗作用。这种联合使用在不增加毒性的情况下，既实现了显著的肿瘤抑制作用，又产生了显著的治愈效果。
Zotero 插件