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[乙醇对家兔摄食及防御动机中枢机制的影响]

[Effect of ethanol on central mechanisms of alimentary and defensive motivation in the rabbit].

作者信息

Zilov V G, Merkur'eva R V, Rogacheva S K, Ivanova L I, Bushinskaia L I

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Nov-Dec;34(6):1159-66.

PMID:6524074
Abstract

A single intravenous administration of ethanol (0.5 g/kg) to rabbits had different effects on the excitability of feeding and defensive motivational centers of the lateral and ventromedial hypothalamus. Ethanol abolished both inhibitory effects of the dorsal hippocampus and facilitatory action of the midbrain reticular formation on alimentary and defensive motivations. It elicited new power distributions of the main rhythms of general electrical cortical activity in the background and under stimulation of limbic-midbrain structures. Analysis of the activity of organello-specific enzymes in limbic-midbrain neurones revealed disturbances of cellular energetic processes caused by ethanol.

摘要

给兔子单次静脉注射乙醇(0.5克/千克),对下丘脑外侧和腹内侧的进食及防御动机中枢的兴奋性产生了不同影响。乙醇消除了背侧海马体对进食和防御动机的抑制作用以及中脑网状结构的促进作用。在背景状态以及边缘 - 中脑结构受到刺激的情况下,它引发了大脑皮层总体电活动主要节律的新功率分布。对边缘 - 中脑神经元中细胞器特异性酶活性的分析揭示了乙醇导致的细胞能量代谢过程紊乱。

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1
[Effect of ethanol on central mechanisms of alimentary and defensive motivation in the rabbit].[乙醇对家兔摄食及防御动机中枢机制的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Nov-Dec;34(6):1159-66.
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[Substance P and the ethanol-evoked changes in the independent motivated behavioral reactions of rabbits].[P物质与乙醇诱发的家兔自主动机行为反应变化]
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Substance P against ethanol-induced alterations in central mechanisms of feeding and escape in rabbits.P物质对乙醇诱导的家兔摄食和逃避中枢机制改变的影响
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