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[体内及体外性类固醇对尿酸与血浆蛋白结合的影响]

[Effect of sex steroids in vivo and in vitro on the binding of uric acid to plasma proteins].

作者信息

Taddeo A, Renieri A, Fioravanti A, Morozzi G, Parrini E, D'Amato M S, Ricci M G

出版信息

Boll Soc Ital Biol Sper. 1984 Sep 30;60(9):1709-14.

PMID:6525290
Abstract

Modifications on the binding of uric acid to human plasma proteins have been studied in regularly menstruating females aged 25-30 years with a normal cycle, in comparison with a group of healthy age-matched males and with a group of post-menopausal females. The binding of uric acid to plasma proteins was estimated using micropartition system Amicon. The results obtained demonstrate a significant increase of uric acid binding during ovulatory and mid-luteal phase of menstrual cycle. No modifications are shown in post-menopausal females and in healthy males. No modifications have been shown with the same experiments performed in vitro.

摘要

在月经周期正常的25至30岁规律行经女性中,研究了尿酸与人体血浆蛋白结合的变化,并与一组年龄匹配的健康男性和一组绝经后女性进行比较。使用Amicon微分离系统评估尿酸与血浆蛋白的结合情况。获得的结果表明,在月经周期的排卵期和黄体中期,尿酸结合显著增加。绝经后女性和健康男性未显示出变化。在体外进行的相同实验中也未显示出变化。

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[Effect of sex steroids in vivo and in vitro on the binding of uric acid to plasma proteins].[体内及体外性类固醇对尿酸与血浆蛋白结合的影响]
Boll Soc Ital Biol Sper. 1984 Sep 30;60(9):1709-14.
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The relationship of sex steroids to uric acid levels in plasma and urine.血浆和尿液中甾体性激素与尿酸水平的关系。
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The sex steroids influence on uric acid binding to human plasma proteins.性类固醇对尿酸与人类血浆蛋白结合的影响。
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Sex Differences in Urate Handling.尿酸处理中的性别差异。
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