Broadbent D E
Br J Clin Pharmacol. 1984;18 Suppl 1(Suppl 1):5S-11S. doi: 10.1111/j.1365-2125.1984.tb02577.x.
Performance involves numerous sub-functions, and cannot be treated as a unit. Several attempts have been made to separate functions impaired by different classes of drug: for example, high (monitoring) vs lower (performing) levels of function, early (perceptual) vs later (motor) functions, and strategic vs executive functions. The practical implications are that one cannot predict effects of a drug from a single performance test. One must either simulate the practical situation exactly, or use a battery of analytical tests to form a profile of effects. The latter is the policy urged in this paper.
行为表现涉及众多子功能,不能被视为一个整体。人们已多次尝试区分受不同类别药物损害的功能:例如,高(监测)与低(执行)水平的功能、早期(感知)与后期(运动)功能,以及策略性与执行性功能。实际意义在于,不能从单一的行为测试来预测药物的效果。必须要么精确模拟实际情况,要么使用一系列分析测试来形成效果概况。后者是本文所倡导的策略。