Kayser V, Guilbaud G
Brain Res. 1984 Dec 3;323(1):144-7. doi: 10.1016/0006-8993(84)90277-4.
In 21 arthritic rats, responses of 128 somatosensory neurons located in the intralaminar region of the thalamus were studied. This study reveals a profound change in the responses of intralaminar neurons in such rats, as compared with those observed in normal animals. Most of the activated neurons (98/120) were driven by moderate mechanical stimulation applied to the joints, while only few neurons (7/120) were exclusively driven by intense mechanical stimuli such as pinch. In addition numerous activated neurons were located in the ascending branch of the CL where in normal rat, few somatosensory 'noxious' neurons have been recorded.
在21只患有关节炎的大鼠中，对位于丘脑板内核层区域的128个躯体感觉神经元的反应进行了研究。这项研究揭示，与正常动物相比，此类大鼠的板内核层神经元反应发生了深刻变化。大多数被激活的神经元（98/120）由施加于关节的中等强度机械刺激驱动，而仅有少数神经元（7/120）仅由捏压等强烈机械刺激驱动。此外，许多被激活的神经元位于CL核的升支，在正常大鼠中，此处记录到的躯体感觉“伤害性”神经元很少。
