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儿童期营养对冠心病发病根源的影响。

Influence of nutrition in childhood on the origins of coronary heart disease.

作者信息

Brook C G

出版信息

Postgrad Med J. 1978 Mar;54(629):171-5. doi: 10.1136/pgmj.54.629.171.

Abstract

Both the quality and the quantity of food ingested are relevant to the genesis of risk factors for coronary heart disease and the two are inseparable. Nevertheless they have a major common pathway through hypertension, which may well be the most important consequence of a high-protein, high-carbohydrate, high-fat, high-energy and high-sodium diet. Because body fatness is a strongly genetically determined characteristic and because it evolves over the whole period of childhood a vigorous and sustained programme of health education is required at all levels. The aim of such a programme is to effect a small shift in the fatness of the whole population; such a shift would dramatically and disproportionately reduce the incidence of obesity. Since the morbidity and mortality which is found in obese subjects arises primarily from cardiovascular disease in general, and coronary heart disease in particular, nutritional influences have obvious relevance to the prevention of coronary heart disease.

摘要

摄入食物的质量和数量都与冠心病危险因素的产生有关,而且二者密不可分。然而,它们有一个通过高血压的主要共同途径,高血压很可能是高蛋白、高碳水化合物、高脂肪、高能量和高钠饮食最重要的后果。由于身体肥胖是一个由基因强烈决定的特征,并且它在整个童年时期都会发展,因此需要在各个层面开展积极且持续的健康教育项目。这样一个项目的目标是使整个人口的肥胖程度发生微小变化;这样的变化将显著且不成比例地降低肥胖症的发病率。由于肥胖人群中发现的发病率和死亡率主要源于一般的心血管疾病,尤其是冠心病,营养因素显然与冠心病的预防相关。

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