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用于婴儿人工喂养的制剂。

Preparations used for the artificial feeding of infants.

作者信息

Widdowson E M

出版信息

Postgrad Med J. 1978 Mar;54(629):176-80. doi: 10.1136/pgmj.54.629.176.

DOI:10.1136/pgmj.54.629.176
PMID:652681
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2425200/
Abstract

Cow's milk differs from human milk in a number of important ways, and manufactures of dried milk preparations for infants have used various methods to make the composition of the diluted product more like that of human milk. The first was to add lactose, or to recommend the mother to add sucrose. This not only increased the carbohydrate, but also 'diluted' the protein and inorganic constituents which are more concentrated in cow's than in human milk. The second was to replace all or part of the cow's milk fat with animal and vegetable fats, and so make the fatty acid composition more like that of human milk fat. In particular the proportion of linoleic acid was increased and that of stearic acid decreased, and this made the fat more easily digested and absorbed by the young infant. The third modification of cow's milk has been more fundamental. Its aim has been to make a product containing less sodium and phosphorus than cow's milk and with a higher lactalbumin: casein ratio. Whey, which contains lactalbumin but not casein, is used as the starting material. This is dialysed to remove soluble inorganic constituents. Some skimmed milk is then added to supply casein and some minerals, and the composition is adjusted as required with further minerals and vitamins. Lactose is added and a mixture of animal and vegetable fats. Dried milks on sale in Britain contain added vitamins A,D, and C and also iron. Some have added copper and zinc.

摘要

牛奶在许多重要方面与母乳不同,婴幼儿奶粉制造商采用了多种方法,使稀释后的产品成分更接近母乳。第一种方法是添加乳糖,或者建议母亲添加蔗糖。这不仅增加了碳水化合物含量,还“稀释”了蛋白质和无机成分,因为这些成分在牛奶中的浓度高于母乳。第二种方法是用动物脂肪和植物油替代全部或部分牛奶脂肪,从而使脂肪酸组成更接近母乳脂肪。特别是亚油酸的比例增加了,硬脂酸的比例降低了,这使得脂肪更易于婴儿消化和吸收。对牛奶的第三种改良更为根本。其目的是生产一种钠和磷含量低于牛奶、乳白蛋白与酪蛋白比例更高的产品。以含有乳白蛋白但不含酪蛋白的乳清为原料。对其进行透析以去除可溶性无机成分。然后添加一些脱脂牛奶以提供酪蛋白和一些矿物质,并根据需要用其他矿物质和维生素调整成分。添加乳糖以及动物脂肪和植物油的混合物。在英国销售的奶粉添加了维生素A、D、C以及铁。有些还添加了铜和锌。

相似文献

1
Preparations used for the artificial feeding of infants.用于婴儿人工喂养的制剂。
Postgrad Med J. 1978 Mar;54(629):176-80. doi: 10.1136/pgmj.54.629.176.
2
"Added lactose" and "added sucrose" cow's milk formulae in nutrition of low birthweight babies.“添加乳糖”和“添加蔗糖”的牛奶配方奶用于低出生体重儿的营养
Arch Dis Child. 1975 Jun;50(6):409-18. doi: 10.1136/adc.50.6.409.
3
Infant formulas.婴儿配方奶粉。
J Am Pharm Assoc. 1975 May;15(5):230-8, 246. doi: 10.1016/s0003-0465(15)32056-5.
4
The composition of human milk.人乳的成分。
Semin Perinatol. 1979 Jul;3(3):225-39.
5
Manganese binding proteins in human and cow's milk.人乳和牛乳中的锰结合蛋白。
Am J Clin Nutr. 1985 Mar;41(3):550-9. doi: 10.1093/ajcn/41.3.550.
6
Bioavailability of zinc and its binding to casein in milks and formulas.锌在牛奶和配方奶中的生物利用度及其与酪蛋白的结合情况。
J Trace Elem Med Biol. 2000 Oct;14(3):146-53. doi: 10.1016/S0946-672X(00)80003-6.
7
Nutrient intakes of formula-fed infants and infants fed cow's milk.配方奶喂养婴儿和牛奶喂养婴儿的营养摄入量。
Pediatrics. 1985 Feb;75(2):343-51.
8
Specialized formulas and feedings for infants with malabsorption or formula intolerance.针对吸收不良或配方奶不耐受婴儿的特殊配方和喂养方式。
J Am Diet Assoc. 1986 Feb;86(2):191-200.
9
Distribution of trace elements and minerals in human and cow's milk.微量元素和矿物质在人乳与牛乳中的分布。
Pediatr Res. 1983 Nov;17(11):912-5. doi: 10.1203/00006450-198311000-00015.
10
[Copper, iron and zinc content of preterm and term human milk and cow's milk].[早产儿母乳、足月儿母乳和牛奶中的铜、铁和锌含量]
Hua Xi Yi Ke Da Xue Xue Bao. 1991 Sep;22(4):428-31.

本文引用的文献

1
Metabolism of vitamin D in animals. V. Isolation of vitamin D sulfate from mammalian milk.动物体内维生素D的代谢。V. 从哺乳动物乳汁中分离硫酸维生素D。
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Body fat of British and Dutch infants.英国和荷兰婴儿的体脂
Br Med J. 1975 Mar 22;1(5959):653-5. doi: 10.1136/bmj.1.5959.653.
3
Body lipids of guinea pigs exposed to different dietary fats from mid-gestation to 3 months of age. II. The fatty acid composition of the lipids of liver, plasma, adipose tissue, muscle and red cell membranes at birth.从妊娠中期到3月龄接触不同膳食脂肪的豚鼠的体脂。II. 出生时肝脏、血浆、脂肪组织、肌肉和红细胞膜脂质的脂肪酸组成。
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Milk protein quantity and quality in low-birth-weight infants. III. Effects on sulfur amino acids in plasma and urine.低体重儿的乳蛋白数量与质量。III. 对血浆和尿液中含硫氨基酸的影响。
J Pediatr. 1977 Mar;90(3):348-55. doi: 10.1016/s0022-3476(77)80692-6.
5
Vitamin-D in human milk.母乳中的维生素D
Lancet. 1977 Jan 22;1(8004):167-8. doi: 10.1016/s0140-6736(77)91764-0.