Kjaeldgaard A, Larsson B
Thromb Res. 1984 Dec 15;36(6):571-8. doi: 10.1016/0049-3848(84)90196-8.
The fibrinolytic activity in the vessel wall (FAV), in plasma and in euglobulin solution (FAE) was determined in rats exposed to cigarette smoke in an inhalation chamber or treated with contraceptive hormones. In the smoke-exposed rats increased FAE and significantly decreased FAV were demonstrated. No effect on fibrinolysis was recorded in the hormone-treated rats, in which mean plasma levels of ethinylestradiol and d-norgestrel were 74 pg/ml and 0.17 ng/ml, respectively, six hours after the last subcutaneous administration.
在吸入室内暴露于香烟烟雾或接受避孕激素治疗的大鼠中，测定了血管壁中的纤溶活性（FAV）、血浆中的纤溶活性和优球蛋白溶液中的纤溶活性（FAE）。在暴露于烟雾的大鼠中，FAE增加，FAV显著降低。在接受激素治疗的大鼠中未记录到对纤溶的影响，在最后一次皮下给药6小时后，这些大鼠的乙炔雌二醇和炔诺孕酮的平均血浆水平分别为74 pg/ml和0.17 ng/ml。
