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肥胖和去势雄性大鼠下丘脑不同区域的儿茶酚胺

Catecholamines in discrete areas of the hypothalamus of obese and castrated male rats.

作者信息

Cruce J A, Thoa N B, Jacobowitz D M

出版信息

Pharmacol Biochem Behav. 1978 Mar;8(3):287-9. doi: 10.1016/0091-3057(78)90318-0.

DOI:10.1016/0091-3057(78)90318-0
PMID:652836
Abstract

Levels of norepinephrine (NE) and dopamine (DA) were measured in eight discrete regions of the hypothalamus in three groups of male rats; genetically obese (fafa), non-obese (FaFa) and castrated non-obese (FaFa). DA levels showed no significant differences among the groups in any of the regions. NE levels in the paraventricular nucleus (PVN) were significantly lower in the obese and castrated animals than in the normal animals. In the median eminence (ME), NE levels were significantly decreased for the castrated group. None of the other regions sampled showed significant differences in NE levels.

摘要

在三组雄性大鼠的下丘脑八个离散区域中测量了去甲肾上腺素(NE)和多巴胺(DA)的水平;这三组分别是遗传性肥胖(fafa)、非肥胖(FaFa)和去势非肥胖(FaFa)大鼠。在任何区域中,各组之间的DA水平均无显著差异。肥胖和去势动物室旁核(PVN)中的NE水平显著低于正常动物。在正中隆起(ME)中,去势组的NE水平显著降低。其他采样区域的NE水平均无显著差异。

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Catecholamines in discrete areas of the hypothalamus of obese and castrated male rats.肥胖和去势雄性大鼠下丘脑不同区域的儿茶酚胺
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