Pleger E, Wuthe H
Z Erkr Atmungsorgane. 1984;163(3):229-40.
Tests were conducted on 90 smokers and a control group of 20 non-smokers using not only simple spirometry but also pneumotachography and the forced oscillation technique, including flow- and resistance-volume graphs. FEV1 was proved to be a sensitive screening test for early recognition of disfunction in the region of the small airways. 39,5% of the younger light smokers already showed signs of impairment to the breathing mechanics indicating exobronchial obstruction. The heavy, mostly older, smokers frequently showed complex disfunction, and in 55,3% the oscillatory resistance revealed quantifiable endobronchial obstruction. The oscillatory flow-resistance-increase-volume (as a percentage of vital capacity) proved the most sensitive small-airways-test during middle age, permitting significant distinction of smokers from non-smokers up to the age of 55.
对90名吸烟者和20名不吸烟者的对照组进行了测试,不仅使用了简单的肺活量测定法,还使用了呼吸流速描记法和强迫振荡技术,包括流量-阻力-容积图。FEV1被证明是一种敏感的筛查测试,可用于早期识别小气道区域的功能障碍。39.5%的年轻轻度吸烟者已经出现呼吸力学受损的迹象,表明存在支气管外阻塞。重度吸烟者,大多为年长吸烟者,经常表现出复杂的功能障碍,55.3%的人振荡阻力显示存在可量化的支气管内阻塞。振荡流阻增加容积(占肺活量的百分比)被证明是中年时期最敏感的小气道测试,能够在55岁之前显著区分吸烟者和不吸烟者。