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[肺量计、呼吸流速描记法和振荡阻力测量法在阻塞性呼吸道疾病功能诊断中的价值]

[Value of spirometric, pneumotachographic and oscilloresistometric studies in the functional diagnosis of obstructive respiratory tract diseases].

作者信息

Pleger E, Wuthe H

出版信息

Z Erkr Atmungsorgane. 1984;163(3):229-40.

PMID:6528652
Abstract

Tests were conducted on 90 smokers and a control group of 20 non-smokers using not only simple spirometry but also pneumotachography and the forced oscillation technique, including flow- and resistance-volume graphs. FEV1 was proved to be a sensitive screening test for early recognition of disfunction in the region of the small airways. 39,5% of the younger light smokers already showed signs of impairment to the breathing mechanics indicating exobronchial obstruction. The heavy, mostly older, smokers frequently showed complex disfunction, and in 55,3% the oscillatory resistance revealed quantifiable endobronchial obstruction. The oscillatory flow-resistance-increase-volume (as a percentage of vital capacity) proved the most sensitive small-airways-test during middle age, permitting significant distinction of smokers from non-smokers up to the age of 55.

摘要

对90名吸烟者和20名不吸烟者的对照组进行了测试,不仅使用了简单的肺活量测定法,还使用了呼吸流速描记法和强迫振荡技术,包括流量-阻力-容积图。FEV1被证明是一种敏感的筛查测试,可用于早期识别小气道区域的功能障碍。39.5%的年轻轻度吸烟者已经出现呼吸力学受损的迹象,表明存在支气管外阻塞。重度吸烟者,大多为年长吸烟者,经常表现出复杂的功能障碍,55.3%的人振荡阻力显示存在可量化的支气管内阻塞。振荡流阻增加容积(占肺活量的百分比)被证明是中年时期最敏感的小气道测试,能够在55岁之前显著区分吸烟者和不吸烟者。

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