Lupetti M, Dolfi A, Malatesta T, Giannessi F
Anat Anz. 1984;157(4):291-7.
The present paper contains data on the morphological modifications present in chicks which, after treatment with testosterone lasting 10 days (from the seventh to the seventeenth days after hatching), were killed on the 30th, 35th, 40th, 50th and 70th day of life; this interval of time might theoretically have allowed a gradual re-establishment of the bursal architecture. Examination of the bursae of Fabricus of the animals treated showed greatly varying pictures. The 2 main types of behaviour were the following: the histological pattern of certain bursae had been completely restored to normal. Others did not act in the same way but wide areas of their plicae proved to be devoid of lymphoid tissue and well-formed lymphoid follicles were observed only in certain places. These 2 kinds of behaviour, and particularly what we observed in the second case, might suggest that, since the lymphoid follicle-associated epithelial cells are the last to disappear after treatment with testosterone propionate and the follicles are restored only where these cells remain, the lymphoid follicle-associated epithelial cells may be considered to be responsible for the re-establishment of the bursal follicle.
本文包含了有关雏鸡形态学变化的数据。这些雏鸡在孵化后第7天至第17天接受了为期10天的睾酮处理，并在出生后的第30天、第35天、第40天、第50天和第70天被处死；从理论上讲，这段时间间隔可能使法氏囊结构逐渐重新建立。对接受处理的动物的法氏囊进行检查，结果显示出大不相同的情况。主要有以下两种行为类型：某些法氏囊的组织学模式已完全恢复正常。其他法氏囊则不然，其皱襞的大片区域没有淋巴组织，仅在某些部位观察到发育良好的淋巴滤泡。这两种行为类型，尤其是我们在第二种情况中观察到的，可能表明，由于淋巴滤泡相关上皮细胞在用丙酸睾酮处理后是最后消失的，并且滤泡仅在这些细胞留存的地方得以恢复，因此可以认为淋巴滤泡相关上皮细胞对法氏囊滤泡的重新建立负责。
