Lupetti M, Dolfi A, Michelucci S
Anat Rec. 1983 Feb;205(2):177-83. doi: 10.1002/ar.1092050208.
Administration of androgens produces damage in lymphoid tissue and in the bursa of Fabricius. After IM administration of 5 mg of testosterone propionate (TP) beginning at hatching and continued during the following 4 days, a significant reduction in the bursal weights is observed. Histologically, an increase in the connective tissue is observed and cystic formations are also found. In all cysts examined, there is continuity of the cystic lumen with the free surface. The follicle-associated epithelial (FAE) cells are on the bottom of the pseudocysts and form a separation between the pseudocystic cavity and the lymphoid tissue which is still further inwards. These cells do not lose their esterase activity, even though they are often flattened. Furthermore, they disappear in the pseudocysts deprived of lymphoid tissue. A new hypothesis is advanced that the FAE cells originate from the mesenchyme with differentiation in the histiocytic line.
雄激素的施用会对淋巴组织和法氏囊造成损害。从孵化开始肌肉注射5毫克丙酸睾酮（TP），并在接下来的4天持续注射，可观察到法氏囊重量显著减轻。组织学上，观察到结缔组织增加，还发现了囊肿形成。在所有检查的囊肿中，囊腔与自由表面相连。滤泡相关上皮（FAE）细胞位于假囊肿底部，在假囊肿腔和更靠内的淋巴组织之间形成分隔。这些细胞即使经常变扁平，也不会丧失其酯酶活性。此外，它们在缺乏淋巴组织的假囊肿中消失。提出了一个新的假说，即FAE细胞起源于间充质，并在组织细胞系中分化。
