Mosca S, Molino D, Magliacano V, Cantone P, Angrisani L
Ann Gastroenterol Hepatol (Paris). 1984 Jul-Sep;20(4):207-9.
Serum gastrin before and after a low-lipid glycoprotein meal was studied in patients with viral cirrhosis (without associated alcoholism) and controls. Cirrhotics are at high risk of peptic ulceration and most authors have attributed this to their gastrin levels which in many studies are higher in cirrhotics than controls. Since such studies involved patients with cirrhosis from a variety of causes, mostly alcohol (which in itself causes a rise in gastrin levels and an increased risk of peptic ulceration), we believed it necessary to evaluate gastrin levels before and after stimulation in patients with non-alcoholic cirrhosis, i.e. in those with viral cirrhosis.
对病毒性肝硬化(无酒精中毒相关因素)患者及对照组在低脂糖蛋白餐后的血清胃泌素水平进行了研究。肝硬化患者发生消化性溃疡的风险很高,大多数作者将此归因于他们的胃泌素水平,在许多研究中,肝硬化患者的胃泌素水平高于对照组。由于此类研究涉及各种病因的肝硬化患者,大多与酒精有关(酒精本身会导致胃泌素水平升高及消化性溃疡风险增加),我们认为有必要评估非酒精性肝硬化患者(即病毒性肝硬化患者)在刺激前后的胃泌素水平。