Pitcock J A, Brown P S, Brooks B, Susic D, Kentera D, Rapp J P, Muirhead E E
J Hypertens. 1984 Aug;2(4):419-25.
The renomedullary interstitial cell (RIC) was studied morphometrically in the partial nephrectomy-salt (Chanutin-Ferris) model of hypertension. The RIC were compared in four strains of rat, two of them being resistant to the induction of this form of hypertension and two of them being sensitive. The Dahl salt-resistant (R/JR) rat was compared to a commercial Sprague-Dawley (SD) strain, and a Wistar derived strain discovered in Belgrade by Susic and Kentera (WB) was compared to a commercial Wistar strain (W). In both studies, resistance and sensitivity correlated well with the state of the RIC before the experimental procedure, the resistant strain having more numerous and better granulated RIC than the sensitive strain. It may therefore be possible to predict salt-resistance or sensitivity in rats by morphological examination of the RIC.
在高血压的部分肾切除-盐（查努廷-费里斯）模型中，对肾髓质间质细胞（RIC）进行了形态计量学研究。在四种大鼠品系中对RIC进行了比较，其中两种对这种高血压形式的诱导具有抗性，另外两种则敏感。将达尔盐抗性（R/JR）大鼠与商业性斯普拉格-道利（SD）品系进行比较，并将苏西奇和肯特拉在贝尔格莱德发现的源自威斯塔的品系（WB）与商业性威斯塔品系（W）进行比较。在两项研究中，抗性和敏感性都与实验程序前RIC的状态密切相关，抗性品系的RIC比敏感品系数量更多且颗粒化更好。因此，通过对RIC进行形态学检查，有可能预测大鼠的盐抗性或敏感性。
