Keates R H, McGowan K A
Ann Ophthalmol. 1984 Dec;16(12):1116-21.
One hundred six consecutive patients undergoing elective cataract surgery were divided into a control group and treatment group in a double-blinded study to evaluate the non-steroidal, anti-inflammatory drug indomethacin as an aid for maintaining pupil dilation during surgery. Both groups received the routine preoperative dilating drops, and the treatment group also received 1% indomethacin. After lens extraction, the change in pupil diameter from the preoperative measurement averaged 0.27 mm in the treatment group and 0.84 mm in the control group. The difference in control groups was significant (p = 0.001), favoring indomethacin for maintaining pupil dilation.
在一项双盲研究中，106例接受择期白内障手术的连续患者被分为对照组和治疗组，以评估非甾体抗炎药吲哚美辛在手术期间辅助维持瞳孔散大的效果。两组均接受常规术前散瞳滴眼液，治疗组还接受1%的吲哚美辛。晶状体摘除术后，治疗组瞳孔直径较术前测量的平均变化为0.27mm，对照组为0.84mm。对照组的差异具有统计学意义（p = 0.001），表明吲哚美辛有利于维持瞳孔散大。
