大鼠视前区冷却诱导棕色脂肪组织产热过程中腹内侧下丘脑的参与。
Involvement of ventromedial hypothalamus in brown adipose tissue thermogenesis induced by preoptic cooling in rats.
作者信息
Imai-Matsumura K, Matsumura K, Nakayama T
出版信息
Jpn J Physiol. 1984;34(5):939-43. doi: 10.2170/jjphysiol.34.939.
PMID:6533384
Abstract
In unanesthetized rats, preoptic (PO) cooling increased brown adipose tissue (BAT) temperature (Tbat). Tbat was kept at a higher level by PO cooling, but lidocaine injected into the ventromedial hypothalamus (VMH) decreased Tbat and saline had no effect. These results indicate VMH is involved in BAT thermogenesis induced by PO cooling.
摘要
在未麻醉的大鼠中，视前区（PO）冷却可提高棕色脂肪组织（BAT）的温度（Tbat）。通过PO冷却可使Tbat维持在较高水平，但向腹内侧下丘脑（VMH）注射利多卡因会降低Tbat，而注射生理盐水则无影响。这些结果表明VMH参与了由PO冷却诱导的BAT产热过程。
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