Kertes P J, Glabus M, Murray A, Julian D G, Campbell R W
Eur Heart J. 1984 Dec;5(12):974-83. doi: 10.1093/oxfordjournals.eurheartj.a061617.
Signal averaging to detect abnormalities in the terminal phase of ventricular depolarization has been performed in several groups of patients with various manifestations of ischaemic heart disease. Late potentials were common in patients with VT and in a group of patients having cardiac surgery. Findings in the surgical group highlighted the close correlation of late potentials with delayed, fragmented epicardial activation supporting the hypothesis that late potentials reflect a myocardial substrate which would support re-entrant VT. The findings in the surgical group allowed a definition of late potentials which could be applied to other patients in the study, and also demonstrated a spectrum of late depolarization abnormalities. Signal averaging is technically feasible in the noisy CCU environment but late potentials were detected in few patients early in AMI. Late potentials were also rarely seen in patients with VF and therefore cannot be construed as a predictive index of this arrhythmia.
在几组患有各种缺血性心脏病表现的患者中，已进行信号平均以检测心室去极化终末阶段的异常情况。室性心动过速（VT）患者以及一组接受心脏手术的患者中常见晚期电位。手术组的研究结果突出了晚期电位与延迟、碎裂的心外膜激动之间的密切相关性，支持了晚期电位反映心肌基质从而支持折返性室性心动过速这一假说。手术组的研究结果使得能够定义可应用于该研究中其他患者的晚期电位，并且还展示了一系列晚期去极化异常情况。在嘈杂的冠心病监护病房（CCU）环境中，信号平均在技术上是可行的，但在急性心肌梗死（AMI）早期很少有患者检测到晚期电位。在心室颤动（VF）患者中也很少见到晚期电位，因此不能将其视为这种心律失常的预测指标。
