Condensation of 1-(4,4-dimethyl-2-piperidon-6-yl)-2-propanone with benzaldehyde derivatives.

Condensation of 1-(4,4-dimethyl-2-piperidon-6-yl)-2-propanone with benzaldehyde derivatives and with cinnamic aldehyde was investigated. Generally, alpha, beta-unsaturated ketones with structures of the (E) -chalcone type were formed. The biological activity of the compounds, particularly given orally, seems to be negligible.