Juraska J M, Wilson C J, Groves P M
J Comp Neurol. 1977 Apr 15;172(4):585-600. doi: 10.1002/cne.901720403.
Three variants of the Golgi method were employed to examine the cell types, their dendritic fields and organization and axonal trajectories within the substantia nigra of albino and hooded rats. In both sagittal and coronal sections, large, medium and small neurons were classified on the basis of soma size, extent of dendritic fileds and dendritic caliber. In general nigral cells have three to five primary dendrites that branch relatively infrequently. Some dendrites of all cell types have thinly scattered spines or varicosities. Small cells, found in all areas of the nucleus, have thin dendrites and small, nondirectional dendritic fields. These are considered to be interneurons. The medium cells found in pars compacta, presumed to be the dopaminergic cells of the nigroneostriatal pathway, send long dendrites into pars reticulata perpendicular to the course of pars compacta. In addition, these cells have a number of dendrites which remain in pars compacta. These cells have axons that run medio-dorsally. No axon collaterals were detected. Both large and medium cells are found in pars reticulata. Cells in the dorso-medial aspect of pars reticulata orient rostro-caudally and roughly perpendicular to the course of pars compacta, while cells in the peripeduncular area show a strict orientation which is parallel to the crus cerebri. Some pars reticulata cells emit axon collaterals while others remain unbranced for their observable lenght. Both large and medium cells are also seen in pars lateralis. These cells send long dendrites ventrally into pars reticulata where they run parallel to the crus cerebri, while some shorter dendrites remain in pars lateralis. In total, the substantia nigra appears to have a layered organization: the superior layer is the cellular pars compacta, the second is the dorso-medial area of pars reticulata where both pars compacta and pars reticulata dendrites run rostro-caudally and dorso-ventrally and the third layer is the peripeduncular region where dendrites from all areas run parallel to the crus cerebri.
采用高尔基方法的三种变体，研究白化大鼠和带帽大鼠黑质内的细胞类型、树突野及其组织以及轴突轨迹。在矢状面和冠状面切片中，根据胞体大小、树突野范围和树突管径，将大、中、小神经元进行分类。一般来说，黑质细胞有三到五个初级树突，分支相对较少。所有细胞类型的一些树突都有稀疏分布的棘或膨体。在核的所有区域都能发现小细胞，它们的树突细，树突野小且无方向性。这些细胞被认为是中间神经元。致密部发现的中型细胞，推测是黑质 - 新纹状体通路的多巴胺能细胞，其长树突垂直于致密部的走向伸入网状部。此外，这些细胞还有一些留在致密部的树突。这些细胞的轴突向内侧背侧走行。未检测到轴突侧支。网状部既有大细胞也有中型细胞。网状部背内侧的细胞呈头尾方向排列，大致垂直于致密部的走向，而脚周区的细胞则呈严格的与大脑脚平行的排列方向。一些网状部细胞发出轴突侧支，而另一些在可观察长度内保持无分支状态。外侧部也能看到大细胞和中型细胞。这些细胞的长树突向腹侧伸入网状部，在那里它们与大脑脚平行走行，而一些较短的树突留在外侧部。总体而言，黑质似乎具有分层组织：上层是细胞性的致密部，第二层是网状部的背内侧区域，致密部和网状部的树突在此处呈头尾方向和背腹方向走行，第三层是脚周区域，来自所有区域的树突在此处与大脑脚平行走行。
