Stramignoni A, Palestro G, Coda R, Micca F B, Stramignoni D
Appl Pathol. 1984;2(2):76-84.
A case of recurrent signet ring cell lymphoma involving a salivary gland is reported. The tumour was centroblastic-centrocytic nodular and diffuse. The cells were vacuolated, oil red, Sudan III, PAS and Alcian blue negative. They displayed the Ia-like antigen but were negative for SIg. Ultrastructurally the vacuoles appeared empty or containing residual membrane and/or myelinoid bodies. Sometimes microvesicles were found in them. The vacuoles were mainly located in the Golgi area but they were also found in mitochondria. Cytoplasmic bodies containing microvesicles were also seen. The case is compared with those of the literature and the significance of the vacuoles is discussed.
报告了一例累及唾液腺的复发性印戒细胞淋巴瘤病例。肿瘤呈中心母细胞-中心细胞性结节状和弥漫性。细胞呈空泡状，油红、苏丹III、PAS和阿尔辛蓝染色均为阴性。它们表达Ia样抗原，但表面免疫球蛋白（SIg）阴性。超微结构上，空泡看起来是空的，或含有残余膜和/或髓样小体。有时在空泡中发现微泡。空泡主要位于高尔基体区域，但也见于线粒体。还可见含有微泡的胞质小体。将该病例与文献中的病例进行了比较，并讨论了空泡的意义。
