Talbot D C, Davies J H, Maclennan K A, Smith I E
ICRF Clinical Oncology Unit, Churchill Hospital, Headington, Oxford.
J Clin Pathol. 1994 Feb;47(2):184-6. doi: 10.1136/jcp.47.2.184.
A case of signet-ring cell lymphoma affecting bone marrow is reported. The tumour presented as multiple lytic lesions in the lumbosacral spine. A bone biopsy specimen showed the typical appearances of signet-ring cell lymphoma, and the cells stained positively with antiserum to CD20, though neither immunoglobulin light or heavy chains could be shown within the vacuoles. The patient subsequently responded to chemotherapy.
报告了一例累及骨髓的印戒细胞淋巴瘤病例。肿瘤表现为腰骶椎的多发溶骨性病变。骨活检标本显示印戒细胞淋巴瘤的典型表现,细胞对CD20抗血清呈阳性染色,尽管在空泡内未显示免疫球蛋白轻链或重链。该患者随后对化疗有反应。