Caruso C, Benvegna S, Palmeri P, Cillari E
Tumori. 1978 Feb 28;64(1):25-31. doi: 10.1177/030089167806400103.
Increased localization (trapping) of lymphocytes occurs in lymphoid organs following antigenic challenge. The effect of peptichemio (PTC) upon lymphocyte trapping in lymph nodes and spleen was investigated: the results demonstrate that the drug diminishes trapping in lymphatic organs. The depression of lymphocyte trapping may provide at least one mechanism whereby PTC achieves it immunosuppressive effects.
抗原刺激后，淋巴细胞在淋巴器官中的定位（滞留）增加。研究了肽化学免疫素（PTC）对淋巴细胞在淋巴结和脾脏中滞留的影响：结果表明，该药物可减少淋巴细胞在淋巴器官中的滞留。淋巴细胞滞留的减少可能至少提供了一种机制，通过该机制PTC实现其免疫抑制作用。
