Balonov M I, Kudritskaia O Iu
Genetika. 1984 Feb;20(2):224-32.
The frequency of dominant lethal mutations (DLM) in the germ cells of male mice exposed to either THO- or gamma-irradiation of 137Cs at the dose of 0.5-3.7 Gr was studied. The distribution of the number of dead embryos in females from the control group as well as that at a dose of irradiation less than 1 Gr, corresponds to the Poisson rule. Spermatids appeared to be more radiosensitive than spermatocytes and spermatozoa. The rate of the effect caused by irradiation of both spermatocytes and spermatids did not depend on the dose rate of gamma-irradiation ranging from 1.10(-3) to 1.7 Gr per min. The linear quadratic formula of aD+bD2 describes the relation of the DLM frequency to the doses of either beta- or gamma-irradiation. The THO RBE increases with the decrease of the dose reaching 2.5 at the D less than 0.1 Gr.
研究了暴露于剂量为0.5 - 3.7戈瑞的钍-230或137铯γ射线照射下的雄性小鼠生殖细胞中显性致死突变（DLM）的频率。对照组以及照射剂量小于1戈瑞的雌性小鼠中死胎数量的分布符合泊松法则。精子细胞似乎比精母细胞和精子对辐射更敏感。精母细胞和精子细胞受到照射所产生的效应速率并不取决于γ射线照射剂量率（范围为每分钟1.10(-3)至1.7戈瑞）。aD + bD2的线性二次公式描述了DLM频率与β或γ射线照射剂量之间的关系。钍-230的相对生物效应（RBE）随着剂量的降低而增加，在剂量小于0.1戈瑞时达到2.5。
