Kenney W L, Kamon E
Eur J Appl Physiol Occup Physiol. 1984;52(2):196-201. doi: 10.1007/BF00433392.
Six essentially hypertensive men (average resting arterial pressure of 150/97 mm Hg) and eight normotensive controls (average resting arterial pressure of 115/73 mm Hg) were tested during 1 h of dynamic leg exercise in a warm environment. The groups were well matched for age, VO2 max, body surface area, weight, and body fat. Environmental conditions were 38 degrees C dry-bulb, 28 degrees C wet-bulb; exercise intensity was approximately 40% VO2 max (85-90 W). There were no significant intergroup differences in core or mean skin temperatures, calculated heat exchange variables, heart, or sweat rates. Blood pressure differences between the groups were maintained (P less than 0.01). The hypertensive group responded with a significantly lower stroke index (P less than 0.01) and cardiac index (P less than 0.01), and a decreased slope of the rise in forearm blood flow (P less than 0.01) due to an higher vascular resistance (P less than 0.01). The combined heat load (M + R + C) presented was not sufficient to override the hypertensives' higher cutaneous vasoconstrictor tone. However, on a practical basis, the hypertensives were able to tolerate exercise in the heat as well as their normotensive counterparts.
六名原发性高血压男性(静息动脉压平均为150/97毫米汞柱)和八名血压正常的对照者(静息动脉压平均为115/73毫米汞柱)在温暖环境中进行了1小时的腿部动态运动测试。两组在年龄、最大摄氧量、体表面积、体重和体脂方面匹配良好。环境条件为干球温度38摄氏度,湿球温度28摄氏度;运动强度约为最大摄氧量的40%(85 - 90瓦)。两组在核心温度或平均皮肤温度、计算出的热交换变量、心率或出汗率方面没有显著差异。两组之间的血压差异持续存在(P < 0.01)。高血压组的每搏输出指数(P < 0.01)和心脏指数(P < 0.01)显著降低,由于血管阻力较高(P < 0.01),前臂血流上升斜率减小(P < 0.01)。所呈现的综合热负荷(代谢产热 + 辐射热 + 对流热)不足以克服高血压患者较高的皮肤血管收缩张力。然而,实际上,高血压患者能够像血压正常的对照者一样耐受热环境中的运动。