Thomassen M S, Rørtveit T, Christiansen E N, Norum K R
Br J Nutr. 1984 May;51(3):315-22. doi: 10.1079/bjn19840038.
The effects of unhydrogenated and partially-hydrogenated marine and rapeseed oils on the relative content of n-6 fatty acids in rat liver phospholipids were studied by gas-liquid chromatography. The type of dietary oil strongly affected the pattern of n-6 fatty acids in the liver phospholipids even after a relatively short feeding period (3 weeks). With diets deficient in linoleic acid, accumulation of the 20:3 n-9 fatty acid was observed in the animals receiving partially hydrogenated oils, but not in the animals receiving the unhydrogenated marine oil which contained relatively high amounts of polyunsaturated fatty acids of the n-3 family. The results presented are in line with reports in the literature that dietary trans fatty acids may inhibit the desaturation-elongation enzyme systems of rat liver. The observed effects did not appear to be directly correlated to the dietary content of very-long-chain monounsaturated fatty acids.
采用气液色谱法研究了未氢化和部分氢化的鱼油及菜籽油对大鼠肝脏磷脂中n-6脂肪酸相对含量的影响。即使在较短的喂养期（3周）后，膳食油的类型也强烈影响肝脏磷脂中n-6脂肪酸的模式。在缺乏亚油酸的饮食中，接受部分氢化油的动物肝脏中观察到20:3 n-9脂肪酸的积累，而接受含有相对大量n-3族多不饱和脂肪酸的未氢化鱼油的动物肝脏中未观察到这种积累。给出的结果与文献报道一致，即膳食反式脂肪酸可能抑制大鼠肝脏的去饱和-延长酶系统。观察到的影响似乎与膳食中极长链单不饱和脂肪酸的含量没有直接关系。
