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慢性应激增强阿扑吗啡诱导的小鼠刻板行为：内源性阿片类物质的参与

Chronic stress enhances apomorphine-induced stereotyped behavior in mice: involvement of endogenous opioids.

作者信息

Cabib S, Puglisi-Allegra S, Oliverio A

出版信息

Brain Res. 1984 Apr 23;298(1):138-40. doi: 10.1016/0006-8993(84)91156-9.

DOI:10.1016/0006-8993(84)91156-9
PMID:6539142
Abstract

Mice subjected to repeated stressful experiences showed an increase in stereotypic climbing behavior induced by apomorphine thus suggesting a modified sensitivity of dopaminergic receptors. Naltrexone, injected before each stressful experience, reversed this effect of chronic stress indicating an involvement of endogenous opioids.

摘要

经历反复应激的小鼠对阿扑吗啡诱导的刻板攀爬行为增加，这表明多巴胺能受体敏感性发生了改变。在每次应激经历前注射纳曲酮可逆转慢性应激的这种效应，表明内源性阿片类物质参与其中。

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Chronic stress enhances apomorphine-induced stereotyped behavior in mice: involvement of endogenous opioids.慢性应激增强阿扑吗啡诱导的小鼠刻板行为：内源性阿片类物质的参与
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A genetic analysis of stereotypy in the mouse: dopaminergic plasticity following chronic stress.小鼠刻板行为的遗传学分析：慢性应激后的多巴胺能可塑性。
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[The effect of dopamine receptor stimulation on the motor and stereotypic activities of mice with different genotypes].[多巴胺受体刺激对不同基因型小鼠运动和刻板行为的影响]
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Bimodal effects of MK-801 on locomotion and stereotypy in C57BL/6 mice.MK-801对C57BL/6小鼠运动和刻板行为的双峰效应。
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