Girard P, Boscher C, Navarro F, Forest A
J Fr Ophtalmol. 1984;7(3):205-9.
52 eyes in 50 patients have been treated for a retinal detachment with a giant tear extending over at least 70 degrees. 27 eyes had an inverted posterior retinal flap covering the posterior pole. Conventional extraocular surgery was performed on 20 eyes. There was no success in 6 folded cases and a 42,85% success rate in 14 non-folded retinas. Endocular surgery by vitrectomy plus internal tamponade using air or silicone oil was done on 32 eyes with an 87,50% success rate at the end of surgery. Post-operative retinal retraction reduced the success rates to 45,45% for non-folded cases and 52,38% with folded retinas. There is no question in our mind about the value of endocular surgery for folded retinas. We think that endocular surgery is also the best choice for non folded retinas because of the excellent initial results. Secondary retraction phenomena are caused by endocular cellular proliferation and membrane formation and contraction. We presently try to minimize these by avoiding excess cryopexy, performing a vitrectomy as complete as possible and treating the reattached retina as soon as possible by argon laser photocoagulation. An efficient and safe antiproliferative drug is definitely needed.
50例患者的52只眼睛因视网膜脱离伴巨大裂孔(延伸至少70度)接受了治疗。27只眼睛有倒置的视网膜后瓣覆盖后极。20只眼睛进行了传统的眼外手术。6例折叠病例手术未成功,14例非折叠视网膜的成功率为42.85%。32只眼睛进行了玻璃体切除术加空气或硅油眼内填充的眼内手术,手术结束时成功率为87.50%。术后视网膜回缩使非折叠病例的成功率降至45.45%,折叠视网膜的成功率降至52.38%。我们认为眼内手术对于折叠视网膜的价值毋庸置疑。由于初始效果极佳,我们认为眼内手术也是非折叠视网膜的最佳选择。继发性回缩现象是由眼内细胞增殖、膜形成和收缩引起的。我们目前试图通过避免过度冷冻治疗、尽可能彻底地进行玻璃体切除术以及尽快用氩激光光凝治疗复位的视网膜来尽量减少这些现象。显然需要一种有效且安全的抗增殖药物。