红细胞污染对人商陆丝裂原诱导的免疫球蛋白合成的影响。
The effects of erythrocyte contamination on pokeweed mitogen induced immunoglobulin synthesis in man.
作者信息
Sigfusson A, Souhami R
出版信息
J Immunol Methods. 1984 Aug 3;72(1):167-70. doi: 10.1016/0022-1759(84)90444-7.
PMID:6540283
Abstract
Red blood cell (RBC) contamination of cultures of peripheral blood mononuclear cells does not suppress pokeweed mitogen (PWM) induced immunoglobulin synthesis. At supra-optimal doses of PWM immunoglobulin production is enhanced in the presence of RBCs. The degree of RBC contamination is a factor to be considered in interpreting the results obtained with PWM induced Ig synthesis in disease.
摘要
外周血单个核细胞培养物中的红细胞（RBC）污染不会抑制商陆丝裂原（PWM）诱导的免疫球蛋白合成。在超最佳剂量的PWM存在下，红细胞的存在会增强免疫球蛋白的产生。红细胞污染程度是解释疾病中PWM诱导的Ig合成所获得结果时需要考虑的一个因素。
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