山羊黄体溶解前后血浆中睾酮和5α-双氢睾酮的浓度及其卵巢切除后的行为影响。

Plasma concentrations of testosterone and 5 alpha-dihydrotestosterone around luteolysis in goats and their behavioural effects after ovariectomy.

作者信息

Homeida A M, Cooke R G

出版信息

J Steroid Biochem. 1984 Jun;20(6A):1357-9. doi: 10.1016/0022-4731(84)90169-9.

Abstract

In non-pregnant goats, increased peripheral plasma concentrations of testosterone and 5 alpha-dihydrotestosterone (DHT) occurred at the start of luteal regression and before the day of oestrus. Intramuscular injections of testosterone (10 mg) in arachis oil to progesterone-primed ovariectomized goats induced oestrous behaviour; similar injections of DHT failed to do so. It is suggested that conversion of testosterone to oestrogens by aromatization induces oestrous behaviour in the goat while reduction of testosterone to DHT does not.

摘要

在未怀孕的山羊中，睾酮和5α-双氢睾酮（DHT）的外周血浆浓度在黄体退化开始时及发情日之前升高。对用孕酮预处理的去卵巢山羊肌内注射花生油中的睾酮（10毫克）可诱导发情行为；类似剂量的DHT注射则不能。这表明，睾酮通过芳香化转化为雌激素可诱导山羊发情行为，而睾酮还原为DHT则不能。