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宫内营养不良对足月儿的影响。一项为期14年的前瞻性研究。

The effect of intrauterine malnutrition on the term infant. A 14-year progressive study.

作者信息

Hill R M, Verniaud W M, Deter R L, Tennyson L M, Rettig G M, Zion T E, Vorderman A L, Helms P G, McCulley L B, Hill L L

出版信息

Acta Paediatr Scand. 1984 Jul;73(4):482-7. doi: 10.1111/j.1651-2227.1984.tb09959.x.

DOI:10.1111/j.1651-2227.1984.tb09959.x
PMID:6540512
Abstract

The developmental outcome of 33 newborn infants with clinical intrauterine malnutrition at birth and 13 clinically well nourished infants from a middle to high socio-economic population have been followed from birth to 12-14 years of age. Psychometric studies revealed a lowering of the IQ score in malnourished infants compared to well nourished infants (104 +/- 15 compared to 121 +/- 13, p less than 0.05) and a need for special education (p less than 0.03). Forty-five percent of the malnourished infants' birth weights were above the 10th percentile on the Colorado Intrauterine Growth Grid. The Full Scale IQ of malnourished infants with BW greater and less than 10th percentile on the Colorado Intrauterine Growth Grid were comparable. Malnourished infants with birth weights greater than 10th percentile had lower IQ scores than well nourished infants (101 +/- 13 compared to 121 +/- 13, p less than 0.006). Thirty-nine percent of the infants with handicaps would have been missed if only infants with birth weights less than 10th percentile were considered high risk.

摘要

对33名出生时临床诊断为宫内营养不良的新生儿以及13名来自中高社会经济群体、临床营养良好的婴儿,从出生到12至14岁进行了发育结局跟踪。心理测量学研究显示,与营养良好的婴儿相比,营养不良的婴儿智商得分较低(分别为104±15和121±13,p<0.05),且需要特殊教育(p<0.03)。45%的营养不良婴儿出生体重高于科罗拉多宫内生长发育标准的第10百分位。科罗拉多宫内生长发育标准中出生体重高于和低于第10百分位的营养不良婴儿的全量表智商相当。出生体重高于第10百分位的营养不良婴儿的智商得分低于营养良好的婴儿(分别为101±13和121±13,p<0.006)。如果仅将出生体重低于第10百分位的婴儿视为高危婴儿,那么39%的有残疾婴儿将会被漏诊。

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