Walther F J, Ramaekers L H, van engelshoven J M
Early Hum Dev. 1981 May;5(2):139-43. doi: 10.1016/0378-3782(81)90045-1.
Twenty five term infants malnourished in utero and 25 matched controls were studied at birth and at 2 1/2-3 1/2 years of age. At birth the infants malnourished in utero had a significant retardation in skeletal maturity in comparison with the control group. At 2 1/2-3 1/2 years of age the average skeletal maturity of the intrauterine malnourished children approached that of the controls. However, those with a length below the national 10th centile still showed a retarded skeletal growth in comparison with those who had reached a length above the 10th centile for age.
对25名宫内营养不良的足月儿和25名匹配的对照组儿童在出生时及2岁半至3岁半时进行了研究。与对照组相比,宫内营养不良的婴儿在出生时骨骼成熟度明显滞后。在2岁半至3岁半时,宫内营养不良儿童的平均骨骼成熟度接近对照组。然而,那些身长低于全国第10百分位数的儿童与那些身长达到年龄第10百分位数以上的儿童相比,骨骼生长仍显滞后。