胰腺癌中视黄醇结合蛋白的研究。
Study of retinol-binding protein in pancreatic cancer.
作者信息
Fabris C, Piccoli A, Meani A, Farini R, Vianello D, Del Favero G, Sturniolo G, Brosolo P, Naccarato R
出版信息
J Cancer Res Clin Oncol. 1984;108(2):227-9. doi: 10.1007/BF00402471.
Abstract
Serum RBP, prealbumin, and zinc were evaluated in normal subjects and patients with pancreatic cancer and chronic pancreatitis. A significant decrease of RPB was found in pancreatic cancer patients compared with controls. A concomitant reduction of prealbumin and zinc was also observed. Multiple regression analysis suggested that the modification of RBP serum levels might be accounted for mainly by diminished prealbumin levels, while the direct role of zinc is negligible.
摘要
在正常受试者、胰腺癌患者和慢性胰腺炎患者中对血清视黄醇结合蛋白（RBP）、前白蛋白和锌进行了评估。与对照组相比，发现胰腺癌患者的RPB显著降低。同时也观察到前白蛋白和锌的减少。多元回归分析表明，RBP血清水平的改变可能主要是由于前白蛋白水平降低所致，而锌的直接作用可忽略不计。
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