胰腺癌中视黄醇结合蛋白的研究。
Study of retinol-binding protein in pancreatic cancer.
作者信息
Fabris C, Piccoli A, Meani A, Farini R, Vianello D, Del Favero G, Sturniolo G, Brosolo P, Naccarato R
出版信息
J Cancer Res Clin Oncol. 1984;108(2):227-9. doi: 10.1007/BF00402471.
Abstract
Serum RBP, prealbumin, and zinc were evaluated in normal subjects and patients with pancreatic cancer and chronic pancreatitis. A significant decrease of RPB was found in pancreatic cancer patients compared with controls. A concomitant reduction of prealbumin and zinc was also observed. Multiple regression analysis suggested that the modification of RBP serum levels might be accounted for mainly by diminished prealbumin levels, while the direct role of zinc is negligible.
摘要
在正常受试者、胰腺癌患者和慢性胰腺炎患者中对血清视黄醇结合蛋白（RBP）、前白蛋白和锌进行了评估。与对照组相比，发现胰腺癌患者的RPB显著降低。同时也观察到前白蛋白和锌的减少。多元回归分析表明，RBP血清水平的改变可能主要是由于前白蛋白水平降低所致，而锌的直接作用可忽略不计。
相似文献
1
Study of retinol-binding protein in pancreatic cancer.胰腺癌中视黄醇结合蛋白的研究。
J Cancer Res Clin Oncol. 1984;108(2):227-9. doi: 10.1007/BF00402471.
2
Identification and verification of transthyretin as a potential biomarker for pancreatic ductal adenocarcinoma.鉴定和验证转甲状腺素蛋白作为胰腺导管腺癌的一个潜在的生物标志物。
J Cancer Res Clin Oncol. 2013 Jul;139(7):1117-27. doi: 10.1007/s00432-013-1422-4. Epub 2013 Apr 2.
3
Clinical significance of promoter methylation status of tumor suppressor genes in circulating DNA of pancreatic cancer patients.胰腺癌患者循环 DNA 中肿瘤抑制基因启动子甲基化状态的临床意义。
J Cancer Res Clin Oncol. 2020 Apr;146(4):897-907. doi: 10.1007/s00432-020-03169-y. Epub 2020 Mar 7.
4
Selected laboratory-based biomarkers for assessing vitamin A deficiency in at-risk individuals.用于评估高危个体维生素A缺乏症的选定实验室生物标志物。
Cochrane Database Syst Rev. 2025 May 28;5:CD013742. doi: 10.1002/14651858.CD013742.pub2.
5
Serum C-reactive protein, procalcitonin, and lactate dehydrogenase for the diagnosis of pancreatic necrosis.血清C反应蛋白、降钙素原及乳酸脱氢酶用于诊断胰腺坏死。
Cochrane Database Syst Rev. 2017 Apr 21;4(4):CD012645. doi: 10.1002/14651858.CD012645.
6
Prevalence of autoimmune pancreatitis in pancreatic resection for suspected malignancy: a systematic review and meta-analysis.疑似恶性肿瘤行胰腺切除术的自身免疫性胰腺炎患病率：系统评价和荟萃分析。
BMC Gastroenterol. 2024 Aug 21;24(1):278. doi: 10.1186/s12876-024-03367-9.
7
Proteomic analysis of pancreatic juice for the identification of biomarkers of pancreatic cancer.胰腺液蛋白质组分析用于鉴定胰腺癌的生物标志物。
J Cancer Res Clin Oncol. 2011 Aug;137(8):1229-38. doi: 10.1007/s00432-011-0992-2. Epub 2011 Jun 21.
8
Home treatment for mental health problems: a systematic review.心理健康问题的居家治疗：一项系统综述
Health Technol Assess. 2001;5(15):1-139. doi: 10.3310/hta5150.
9
DJ-1, a novel biomarker and a selected target gene for overcoming chemoresistance in pancreatic cancer.DJ-1，一种新型生物标志物和选择的胰腺癌克服化疗耐药性的靶基因。
J Cancer Res Clin Oncol. 2012 Sep;138(9):1463-74. doi: 10.1007/s00432-012-1205-3. Epub 2012 Apr 19.
10
Duodenum-preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis.保留十二指肠的胰腺切除术与胰十二指肠切除术治疗慢性胰腺炎的对比
Cochrane Database Syst Rev. 2016 Feb 3;2(2):CD011521. doi: 10.1002/14651858.CD011521.pub2.
引用本文的文献
1
Investigating Causal Associations of Diet-Derived Circulating Antioxidants with the Risk of Digestive System Cancers: A Mendelian Randomization Study.探讨饮食来源的循环抗氧化剂与消化系统癌症风险之间的因果关联：一项孟德尔随机化研究。
Nutrients. 2022 Aug 8;14(15):3237. doi: 10.3390/nu14153237.
2
The application of a three-step proteome analysis for identification of new biomarkers of pancreatic cancer.一种三步蛋白质组分析方法在胰腺癌新生物标志物鉴定中的应用。
Int J Proteomics. 2011;2011:628787. doi: 10.1155/2011/628787. Epub 2011 Oct 17.
3
Effects of protein depletion on NK cell cytotoxicity and bone marrow cellularity.蛋白质缺乏对自然杀伤细胞细胞毒性和骨髓细胞数量的影响。
Med Oncol Tumor Pharmacother. 1985;2(3):195-202. doi: 10.1007/BF02934548.
本文引用的文献
1
The serum levels of some trace and bulk elements in cancer patients.癌症患者体内某些微量元素和常量元素的血清水平。
Oncology. 1982;39(1):38-41. doi: 10.1159/000225602.
2
The retinol-binding protein.视黄醇结合蛋白。
Scand J Clin Lab Invest Suppl. 1980;154:45-61.
3
Zinc and copper levels in plasma, erythrocytes, and whole blood in cancer patients.
Klin Wochenschr. 1982 Apr 1;60(7):375-7. doi: 10.1007/BF01721629.
4
Vitamin A and retinol-binding protein in patients with myelomatosis and cancer of epithelial origin.骨髓瘤病和上皮源性癌症患者体内的维生素A和视黄醇结合蛋白
Eur J Cancer Clin Oncol. 1982 Apr;18(4):339-42. doi: 10.1016/0277-5379(82)90003-7.
5
Comparison of retinol-binding protein and beta 2-microglobulin determination in urine for the early detection of tubular proteinuria.尿液中视黄醇结合蛋白和β2-微球蛋白测定用于早期检测肾小管性蛋白尿的比较。
Clin Chim Acta. 1982 Nov 24;126(1):1-7. doi: 10.1016/0009-8981(82)90356-4.
6
The effects of diseases of the liver, thyroid, and kidneys on the transport of vitamin A in human plasma.肝脏、甲状腺和肾脏疾病对人体血浆中维生素A转运的影响。
J Clin Invest. 1971 Nov;50(11):2426-36. doi: 10.1172/JCI106741.
7
Determination of serum zinc concentrations in normal adult subjects by atomic absorption spectrophotometry.
Am J Clin Pathol. 1972 Apr;57(4):506-10. doi: 10.1093/ajcp/57.4.506.
8
Immunochemical quantitation of antigens by single radial immunodiffusion.通过单向辐射免疫扩散法对抗原进行免疫化学定量。
Immunochemistry. 1965 Sep;2(3):235-54. doi: 10.1016/0019-2791(65)90004-2.
9
Vitamin A, zinc and lung cancer.维生素A、锌与肺癌
Br J Cancer. 1979 Dec;40(6):927-31. doi: 10.1038/bjc.1979.287.
10
Plasma vitamin A transport and visual dark adaptation in diseases of the intestine and liver.
Scand J Clin Lab Invest. 1978 Jun;38(4):301-8. doi: 10.3109/00365517809108428.
Zotero 插件