Panksepp J, Normansell L, Siviy S, Rossi J, Zolovick A J
Peptides. 1984 Jul-Aug;5(4):829-31. doi: 10.1016/0196-9781(84)90030-5.
Intraventricular administration of various chain length casomorphins (CM) reliably reduced separation induced distress vocalizations (DVs) in young domestic chicks. At a dose of 50 nanomoles, CM-5 was more potent than either CM-4 or CM-7, but for each the duration of action was approximately half an hour, with CM-7 having a somewhat longer effect. This suppression of DVs was partially antagonized by naloxone (1 mg/kg).
向雏鸡脑室内注射不同链长的酪蛋白吗啡（CM）能可靠地减少因隔离引起的应激性鸣叫（DVs）。在50纳摩尔的剂量下，CM - 5比CM - 4或CM - 7更有效，但每种的作用持续时间约为半小时，CM - 7的作用时间稍长。纳洛酮（1毫克/千克）能部分拮抗这种对DVs的抑制作用。
