Phoenix C H, Chambers K C, Jensen J N, Baughman W
Horm Behav. 1984 Dec;18(4):393-9. doi: 10.1016/0018-506x(84)90025-4.
A 17-year-old, prenatally androgenized (ovariectomized) female rhesus macaque was studied. She had achieved penile intromission and ejaculated when treated with testosterone propionate and paired with a receptive female. To test the extent of behavioral defeminization, a vagina was created through surgical intervention and daily injections of 20 micrograms of estradiol benzoate were given. When she was paired with a male on Day 28 of treatment, she proved receptive to his invitations to copulate and the male achieved intromission. The results indicate that prenatal testosterone may morphologically and behaviorally masculinize the genetic rhesus female without eliminating the capacity to respond as a female under appropriate hormonal and environmental stimulation.
对一只17岁、产前雄激素化(卵巢切除)的雌性恒河猴进行了研究。在接受丙酸睾酮治疗并与一只处于接受期的雌性配对时,它实现了阴茎插入并射精。为了测试行为去雌性化的程度,通过手术干预创建了一个阴道,并每天注射20微克苯甲酸雌二醇。在治疗的第28天,当它与一只雄性配对时,它表现出对雄性交配邀请的接受性,雄性实现了插入。结果表明,产前睾酮可能在形态和行为上使恒河猴雌性基因雄性化,而不会消除在适当的激素和环境刺激下作为雌性做出反应的能力。