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[低浓度苯胺暴露工人的个体剂量测定与生物监测]

[Individual dosimetry and biologic monitoring of workers exposed to low concentrations of aniline].

作者信息

Seghizzi P, Mosconi G, Vitali M T, Beni L, Mandelli A, Pogna R, Pozzoli L

出版信息

G Ital Med Lav. 1984 Sep-Nov;6(5-6):189-99.

PMID:6545208
Abstract

Low aniline vapours concentration exposure has been studied through either active or passive individual dosimeter, in a group of workmen employed in the production of an antioxidant for the rubber industry. We collected 28 samples, confirming the clear correlation existing between the two methods which was already demonstrated in a previous work. We newly suggest the usefulness of the individual passive dosimeter instead of the traditional vacuum pump system. Meanwhile we have determined bound and free aniline and total aromatic amines, with and without an extractive method on column, on urinary samples collected before and after the workshift. The values so obtained have been compared with the results of the active individual dosimetry. We could demonstrated a statistical significative correlation only between urinary aniline determination and the level of exposure, so confirming the value of this parameter as biological indicator of occupational exposure.

摘要

通过主动或被动个体剂量计,对一组从事橡胶工业抗氧化剂生产的工人进行了低浓度苯胺蒸气暴露研究。我们收集了28个样本,证实了这两种方法之间存在明显的相关性,这在之前的一项研究中已经得到证明。我们新提出了个体被动剂量计相较于传统真空泵系统的实用性。同时,我们在轮班前和轮班后采集的尿液样本上,采用和不采用柱萃取法,测定了结合态和游离态苯胺以及总芳香胺。如此获得的值已与主动个体剂量测定的结果进行了比较。我们仅能证明尿液苯胺测定与暴露水平之间存在统计学显著相关性,从而证实了该参数作为职业暴露生物指标的价值。

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