Dolan R J
Wellcome Trust Centre for Neuroimaging, Univeresity College London, London WC1N 3BG.
Ann N Y Acad Sci. 2007 Dec;1121:1-9. doi: 10.1196/annals.1401.020. Epub 2007 Sep 10.
The importance of orbitofrontal cortex (OFC) in human behavioral regulation is no longer a matter of dispute, though its precise role remains a matter of ongoing investigation. It is ironic that this revaluation of OFC required a major departure from a historical nadir, during which it was viewed as redundant or "silent cortex," a situation that prevailed even up to the latter half of the 20th century. The increasing wealth of data from diverse fields within neuroscience now provides an unambiguous testament to the importance of this cortical region in behavioral regulation and cognition in general.
眶额叶皮质（OFC）在人类行为调节中的重要性已不再有争议，尽管其确切作用仍在不断研究中。具有讽刺意味的是，对OFC的这种重新评估需要从历史最低点大幅偏离，在那段时间里，它被视为多余的或“沉默的皮质”，这种情况甚至一直持续到20世纪后半叶。现在，来自神经科学不同领域的越来越多的数据明确证明了这个皮质区域在行为调节和一般认知中的重要性。
