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Heterophile antibodies in sera of patients with Chediak-Higashi syndrome.

作者信息

Tamura T, Merino F, Kano K, Ramirez-Duque P, Milgrom F

出版信息

Int Arch Allergy Appl Immunol. 1984;73(2):186-8. doi: 10.1159/000233463.

DOI:10.1159/000233463
PMID:6546376
Abstract

Sera of 6 patients with Chediak-Higashi syndrome and sera of their mothers were studied for heterophile antibodies. Sera of 5 patients as well as 5 sera of their mothers contained antibodies against trypsinized bovine erythrocytes, tissue sediments of guinea pig kidney or high molecular weight glycoprotein (HMWGP) of bovine erythrocyte stromata. The antibodies combining with HMWGP in enzyme immunoassay belonged to IgM and IgG classes. Although none of the sera had significant titer of agglutinins against sheep erythrocytes, on the basis of absorption and inhibition studies, these antibodies seemed to belong to the Hanganutziu-Deicher group of antibodies.

摘要

相似文献

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