Nistal M, Regadera J, Paniagua R
Arch Pathol Lab Med. 1984 Jul;108(7):579-83.
The testes of two premature newborns and a 9-year-old boy with cystic dysplasia were studied by light and electron microscopy. The histologic pattern of the three cases was similar, differing principally in the extension of the characteristic lesion. This consisted of multiple, anastomosing, irregular cystic spaces of varying sizes and shapes, separated by incomplete connective-tissue septa. The cysts were predominantly located in the mediastinum testis, and spread irregularly, displacing the testicular parenchyma, which was consequently compressed under the tunica albuginea. Electron microscopic examination revealed two types of epithelial cells (flattened and tall cells) lining the cystic spaces. These cells were similar to those lining the normal adult rete testis. Since the rete testis originates from the gonadal blastema, and the efferent ductules from the mesonephric ducts, an embryologic defect in the connection between both structures might be responsible for this lesion.
对两名早产新生儿和一名患有囊性发育异常的9岁男孩的睾丸进行了光镜和电镜研究。这三例的组织学模式相似，主要区别在于特征性病变的范围。其特征为多个大小和形状各异的相互吻合的不规则囊性间隙，由不完整的结缔组织间隔分隔。囊肿主要位于睾丸纵隔，并不规则扩散，挤压睾丸实质，导致其在白膜下受压。电镜检查显示囊性间隙内衬有两种上皮细胞（扁平细胞和高柱状细胞）。这些细胞与正常成年睾丸网内衬的细胞相似。由于睾丸网起源于生殖腺胚基，而输出小管起源于中肾管，这两个结构之间连接的胚胎学缺陷可能是导致该病变的原因。
