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暴露个体尿液中顺式-1,3-二氯丙烯的N-乙酰半胱氨酸共轭物排泄情况。

Urinary excretion of the N-acetyl cysteine conjugate of cis-1,3-dichloropropene by exposed individuals.

作者信息

Osterloh J D, Cohen B S, Popendorf W, Pond S M

出版信息

Arch Environ Health. 1984 Jul-Aug;39(4):271-5. doi: 10.1080/00039896.1984.10545848.

Abstract

A gas chromatographic-mass spectrometric assay was developed to identify and measure the N-acetyl cysteine conjugate of cis-1,3-dichloropropene. The assay was used to show that individuals exposed to 1,3-dichloropropene vapor during field applications excrete this conjugate in their urine. The recoveries of the conjugate were correlated with the product of airborne concentrations and the duration of exposure (r = 0.83).

摘要

开发了一种气相色谱-质谱分析法来鉴定和测量顺式-1,3-二氯丙烯的N-乙酰半胱氨酸共轭物。该分析法用于表明在现场应用期间接触1,3-二氯丙烯蒸气的个体在其尿液中排泄这种共轭物。共轭物的回收率与空气中浓度和暴露持续时间的乘积相关(r = 0.83)。

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