Moragues J, Beneyto J E, Fábregas J L, Spickett R G
Arzneimittelforschung. 1984;34(10A):1346-9.
A new crystalline hydrated aluminium-magnesium hydroxycarbonate, almagate (Almax) is described. It has been shown to have an empirical formula Al2 Mg6(OH)14(CO3)2 X 4 H2O X. X-ray diffraction spectra indicate that it is different from other related antacids and that its crystal structure is made up of brucite layers, in which magnesium is replaced by aluminium in the ratio of 3 to 1, interposed with negatively charged layers containing carbonate ions and water. Analysis of the IR spectra suggests that the interstitial carbonate is coordinated to both metals. Differential thermal analysis demonstrates that almagate has good thermal stability and measurement of its antacid activity shows that it has a rapid neutralization velocity and a high acid consuming capacity.
描述了一种新的结晶水合铝镁羟基碳酸盐——铝镁加（Almax）。已证明其经验式为Al2Mg6(OH)14(CO3)2·4H2O·X。X射线衍射光谱表明它与其他相关抗酸剂不同，其晶体结构由水镁石层组成，其中镁被铝以3比1的比例取代，中间夹有含碳酸根离子和水的带负电层。红外光谱分析表明间隙碳酸盐与两种金属都配位。差示热分析表明铝镁加具有良好的热稳定性，其抗酸活性测定表明它具有快速的中和速度和高的酸消耗能力。
