Parker F, Migliore-Samour D, Floc'h F, Zerial A, Werner G H, Jollès J, Casaretto M, Zahn H, Jollès P
Eur J Biochem. 1984 Dec 17;145(3):677-82. doi: 10.1111/j.1432-1033.1984.tb08609.x.
A hexapeptide obtained from human casein by enzymatic digestion has been purified, sequenced and synthesized; its structure is: Val-Glu-Pro-Ile-Pro-Tyr. In vitro this hexapeptide stimulates the phagocytosis of opsonized sheep red blood cells by murine peritoneal macrophages. Administered intravenously to adult mice, it enhances the resistance to infection with Klebsiella pneumoniae.